Succinate Dehydrogenase

A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.

Also Known As:

Fumarate Reductase; Succinic Dehydrogenase; Dehydrogenase, Succinate; Dehydrogenase, Succinic; Oxidase, Succinic; Reductase, Fumarate; Succinic Oxidase

Macromolecular Substances: 97
- Multiprotein Complexes: 125
  - Multienzyme Complexes: 8
    - Succinate Cytochrome c Oxidoreductase: 31
      - Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1929
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Succinate Cytochrome c Oxidoreductase: 31
      - Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1929
    - Oxidoreductases Acting on CH-CH Group Donors
      - Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1929
  - Multienzyme Complexes: 8
    - Electron Transport Chain Complex Proteins
      - Electron-Transferring Flavoproteins: 82
        Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1929
      - Succinate Cytochrome c Oxidoreductase: 31
        Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1929
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Iron-Binding Proteins: 172
      - Nonheme Iron Proteins
        Iron-Sulfur Proteins: 42
        Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1929
  - Membrane Proteins: 10078
    - Electron Transport Chain Complex Proteins
      - Electron-Transferring Flavoproteins: 82
        Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1929
      - Succinate Cytochrome c Oxidoreductase: 31
        Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1929
  - Flavoproteins: 234
    - Electron-Transferring Flavoproteins: 82
      - Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1929
  - Metalloproteins: 164
    - Iron-Binding Proteins: 172
      - Nonheme Iron Proteins
        Iron-Sulfur Proteins: 42
        Electron Transport Complex II: 20
        Succinate Dehydrogenase: 1929

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Disease

Drug/Important Bio-Agent (IBA)